Medical Artificial Intelligence

Artificial Intelligence (AI) has become a powerful and pervasive technology in recent years, influencing numerous aspects of our daily lives. We encounter AI through recommendation algorithms in online stores, voice-activated smartphone assistants, or the widespread use of technologies like ChatGPT. However, its rapid growth and integration into society raise complex questions and concerns among the public. Public opinions on AI vary widely; while some people are enthusiastic about its potential to revolutionize industries and enable breakthroughs in fields such as medicine, others fear that AI could lead to undesirable outcomes, such as a loss of human control or privacy. These views are often shaped by media narratives and the competing interests of different stakeholders, which play a significant role in influencing both public opinion and policy decisions.

Our team of scientists and communication experts aims to enhance the understanding of AI technologies among the Swiss people, with a particular focus on teenagers and female students, to create a positive societal impact. Building on the foundations of our previous project, NewsOnAI, we will expand beyond traditional media such as newspapers and employ diverse methods, including artistic performances and interactive exhibitions. We will design these activities to be highly interactive, encouraging active participation and dialogue. Activities will include themed theater plays that explore AI’s impact on everyday life, exhibitions where participants can interact with AI tools, and workshops specifically designed for teenagers and female students to discuss AI’s future role in society. Feedback collected will include real-time audience reactions, structured questionnaires, and focus group discussions, which will be analyzed to continuously refine and adapt our engagement strategies.

Our primary audience includes Swiss citizens interested in cultural activities, particularly teenagers who are keen to follow new trends. Additionally, we are committed to addressing gender aspects by designing content and activities that specifically appeal to female students. We aim to inspire and empower young women to take on more prominent roles in shaping the digital world, acknowledging that they have historically been underrepresented in these fields. As societal attention shifts toward greater inclusion, our project will contribute to fostering a more balanced and equitable digital future.

While many individuals in our target groups may lack in-depth technical knowledge of AI, they often encounter new AI products, companies, and social issues through various media channels, including newspapers and science fiction movies. As a result, they may be aware of recent developments but also susceptible to misunderstandings and controversies related to technologies such as ChatGPT, Elon Musk's brain-chip startup, and other emerging AI applications. It is crucial to recognize that media portrayal significantly influences public opinion on AI, both positively and negatively. Media creators, even if they are not experts in AI, often produce content that captures public attention, which high-profile figures, including entrepreneurs, CEOs, and politicians, may leverage to advance their agendas. This can sometimes lead to skewed public perceptions, whether intentionally or unintentionally. Given this landscape, it is essential for AI scientists to collaborate with media creators, providing evidence-based insights to ensure accurate and balanced information is shared with the public. Our project fosters such collaboration, ensuring that both the potential and limitations of AI are clearly communicated. By sharing our findings through diverse media outlets, we aim to reach a broad audience, extending beyond Switzerland. Furthermore, our proactive engagement efforts will foster dynamic, two-way communication between scientists and the public, using interactive methods in exhibitions and theater plays to engage teenagers and female students specifically. Analyzing the feedback from these initiatives will provide invaluable insights into public perspectives on emerging technologies. This understanding will guide scientists in pursuing research directions that effectively address societal concerns, demonstrating the tangible benefits of our project for both scientific advancement and societal well-being. We anticipate that our efforts will have a multiplying social impact over time, promoting informed public discourse and a deeper understanding of AI technologies.

Project DREAM aims to develop a scalable foundation model for multi-channel EEG signal analysis, spanning from basic polysomnography to high-density and intracranial recordings. The goal is to create a unified AI model capable of adapting to various EEG configurations while maintaining simplicity, interpretability, and computational efficiency. By leveraging convolutional neural networks and attention mechanisms, the model will extract robust features for diverse tasks, including sleep stage classification, epilepsy detection, and cognitive function assessment. Collaborations with leading hospitals will provide real-world datasets for validation, ensuring the model’s generalization. Ultimately, this project seeks to advance AI-driven biomedical signal processing, enhancing diagnostic and monitoring capabilities in neurology and sleep medicine.

The algorithmic bias remains one of the key challenges for the wider applicability of Machine Learning (ML) in healthcare. Statistical modeling of natural phenomena has gained traction due to increased representation capacity and data availability. In medicine, particularly, the use of ML models has increased significantly in recent years, especially to support large scale screening, and diagnosis. However impactful, the study of demographic bias of newly developed or already deployed ML solutions in this domain remains largely unaddressed. This is particularly true in the medical imaging domain, where it remains challenging to associate demographic attributes with features. Out of the most recent results, the "impossibility of fairness" establishes some criteria for demographic impartiality cannot be reached simultaneously. Among other factors, the lack of raw data, in particular for intersections of minorities, is one of the greatest issues that remain unaddressed due to their challenging nature. This proposal addresses three important challenges in the domain of ML fairness for medical imaging: (i) Create novel ways to train ML models for medical imaging tasks, that can be automatically adjusted to become more useful (maximize performance), group or individually fair, (ii) Quantify fairness boundaries of ML models and associated development data, and finally, (iii) Build systems whose joint performance with humans in the decision loop is fair towards various individuals and demographic groups. To achieve these goals, we will develop a novel evaluation framework and loss functions that take into account model utility together with all aspects of demographic fairness one may wish to address. A generative framework, trained to isolate tunable demographic features, will provide large-scale data simulation covering minorities and intersections. We will then study fairness (safety) boundaries through a modified learning curve setup, analyzing and quantifying limits in both ML models and training data. Finally, we will study how humans-in-the-decision-loop affect the fairness of hybrid human-AI systems, and address post-deployment utility/fairness tuning by embedding weight coefficients directly into the trained model. The development of methods and tools to detect, mitigate, or remove bias will improve the safety of ML models deployed in healthcare. We expect our work will help define new operational boundaries for the responsible deployment of artificial intelligence tools.